Name:Doxycycline Hyclate
CAS:24390-14-5
MF:C22H26N2O9
The detailed specifications are as below:
| Items | Specification | Result | |
| Appearance | Yellowcrystallinepowderhygroscopic | conforms | |
| Solubility | Itisfreelysolubleinwaterormethanol,sparinglysolubleinethanol(96%),indissolvesinsolutionsofalkaliinhydroxidesandcarbonates | conforms | |
| Identification | Examinethechromatogramsobtainedintheassay | conforms | |
| Reactionwithsulphuricacid | conforms | ||
| Reactionwithofchlorides | conforms | ||
| PH | 2.0~3.0 | 2.4 | |
| SpecificOpticalRotation | -105°~-120° | -112° | |
| Specificabsorbance(349nm) | 300~335 | 318 | |
| Light-absorbingimpurities(490nm) | ≦0.07 | 0.02 | |
| Related Substances | ImpurityA(6-epidoxycycline | ≦2.0% | 1.76% |
| ImpurityB(Metacycline) | ≦2.0% | 0.16% | |
| ImpurityC | ≦0.5% | Notfound | |
| ImpurityD | ≦0.5% | Notfound | |
| Related Substances | ImpurityE | ≦0.5% | Notfound |
| ImpurityF | ≦0.5% | 0.35% | |
| Anyotherimpurity | ≦0.5% | Notfound | |
| Ethanol | 4.3%~6.0% | 5.1% | |
| HeavyMetals | LessThan50ppm | <30ppm | |
| Water | 1.4％to2.8％ | 1.9% | |
| SulfatedAsh | ≦0.4% | conforms | |
| Assay | 95.0%~102.0% | 97.3% | |