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Cyanocobalamin (Vit B12)

Nme:Cyanocobalamin (Vit B12)
CAS:68-19-9
MF:C63H88CoN14O14P
The detailed specifications are as below:

ItemoftestingSpecificationResult
AppearanceDark-redcrystallinepowderorcrystalsconforms
RatioofopticaldensityA361/A550nm3.15~3.403.28
A361/A278nm1.70~1.881.86
TLCconformsconforms
Chemicalpositivepositive
HPLCTheretentiontimeofmajorpeakofthesamplesolutioncorrespondstothatofthestandardsolutionCorrespond
Relatedsubstances
Totalimpurities,%≦3.0%1.6%
Singleimpurities
7β,8β-lactocyanocobalamin,%≦1.0%0.3%
50-carboxycyanocobalamin,%≦0.5%Notdetected
34-methylcyanocobalamin,%≦2.0%0.5%
32-carboxycyanocobalamin≦1.0%Notdetected
8-Epi-cyanocobalamin≦1.0%Notdetected

ItemoftestingSpecificationResult
Anyotherunidentifiedimpurity,%≦0.5%0.3%
Lossondrying,%≦12.0%2.2%
Assayondriedbasis,%96.0~102.0%99.0%
Residualsolvents
Acetone,ppm≦1000ppm16ppm
Ethanol,ppm≦1000ppm2.1×102ppm
ConclusionThisproductcompliedwiththespecificationsofUSP36andPh.Eur.7.0